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What is SPG4?

SPG4 is the most common subtype of a group of rare neurologic disorders called HSP, or Hereditary Spastic Paraplegia. The primary symptom of HSP is difficulty walking due to muscle weakness and tightness (spasticity) in the legs. The severity of symptoms usually worsens over time.


Cure SPG4

A foundation committed to finding a cure

for a rare neurologic disease called

SPG4 Hereditary Spastic Paraplegia.

About SPG4

Find out what SPG4 Hereditary Spastic Paraplegia is.

Our Mission

Learn about our story, our kids and our mission.


Learn about research projects we currently support.


Donate to help fund research to find a cure for SPG4.


Who We Are

Cure SPG4 Foundation was founded in 2020 by two families with young children who were diagnosed with SPG4 Hereditary Spastic Paraplegia.

Our mission is to increase awareness of SPG4 Hereditary Spastic Paraplegia, provide a resource for patients and their families, and fund research to find a cure for SPG4 Hereditary Spastic Paraplegia. 


We Are SPG4

SPG4 has affected the lives of each and every one

of these amazing individuals and their families.  

No one deserves to live with this disease. 

We will not stop fighting for a cure!

We want to see more of you!

Please email for information

about how to have yourself or your child featured on our website.

Caring Child

You can help find a cure today. 

It is critical for affected individuals, their families, and generous donors to help fund the research necessary to help find a cure. Through the generosity of selfless donors, we can help thousands of deserving children, adults, and their families that have been devastated by SPG4 Hereditary Spastic Paraplegia.

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